Detailed analysis of health status of Q fever patients 1 year after the first Dutch outbreak: a case-control study.
نویسندگان
چکیده
BACKGROUND Q fever is a zoonosis caused by the obligate intracellular bacterium Coxiella burnetii. The two long-term complications, after primary infection, are chronic Q fever in ∼1% of patients, and a chronic fatigue syndrome in 10-20%. However, the existence of a protracted decreased health status after Q fever remains controversial. AIM To determine the health status of the patients of the Q fever outbreak in The Netherlands in 2007, 1 year after primary infection. DESIGN Cross-sectional case-control study. METHODS Health status of the patients from the 2007 Dutch Q fever outbreak was compared to age-, sex- and geographically matched and Q fever seronegative controls. Health status of both patients and controls was assessed with the Nijmegen Clinical Screening Instrument (NCSI). RESULTS Fifty-four Q fever patients provided 34 years of age- and sex-matched controls from the same neighbourhood. Eleven controls had positive Q fever serology and were excluded. Q fever patients had significantly more problems on the subdomains of symptoms and functional impairment. Overall quality of life was decreased in both patients and controls, 59% vs. 39%, respectively, ns). Severe fatigue levels were present in 52% of patients vs. 26% in controls (P < 0.05). CONCLUSION These data support a sustained decrease in many aspects of health status in Q fever patients in The Netherlands, 1 year after primary infection.
منابع مشابه
Serious long-term health consequences of Q-fever and Legionnaires' disease.
BACKGROUND We assessed and compared the long-term health status of Q-fever patients and patients with Legionnaires' disease. METHODS Q-fever patients and patients with Legionnaires' disease fulfilling the Dutch notification criteria filled out a questionnaire at one year after onset of illness. The proportion of patients with an abnormal score was calculated for 12 health status subdomains an...
متن کاملOne-year follow-up of patients of the ongoing Dutch Q fever outbreak: clinical, serological and echocardiographic findings
PURPOSE In 2007, a large goat-farming-associated Q fever outbreak occurred in the Netherlands. Data on the clinical outcome of Dutch Q fever patients are lacking. The current advocated follow-up strategy includes serological follow-up to detect evolution to chronic disease and cardiac screening at baseline to identify and prophylactically treat Q fever patients in case of valvulopathy. However,...
متن کاملEvaluating the Status of Patients Suffering from Diarrhea During the Outbreak Occurred in Shahrekord in 2015
Introduction: The term diarrheal diseases, a conventional expression and is neither an epidemiological subject nor a class of diseases, because diarrhea is a symptom of many diseases, however, it is defined as the passage of three or more loose or liquid stools per day. Materials and methods: This is a cross-sectional study in which the records of all patients with symptoms of diarrhea encou...
متن کاملThe health system response to Eltor cholera outbreak: an experience in Iran
Background: Following the outbreak of eltor cholera in Iraq’s Kurdistan, Iran was threatened through the western border. Therefore, the aim of the present study was to evaluate the health system response of Marivan city in Kurdistan Province (Iran) as a risky gateway for the outbreak of eltor cholera epidemic in Iran. Materials and Methods: This cross-sectional study was implemented in...
متن کاملEvaluation of Hepatitis A Outbreak in Boroujerd during 2019: A Case-Control Study
Background and Objectives: Viral hepatitis is one of the most prevalent diseases and an important underlying cause of death and disability in the world. This case-control study was conducted to investigate the outbreak of hepatitis A in Boroujerd in 2019. Methods: This case-control study was conducted to investigate the epidemic of hepatitis A in Boroujerd in 2019. Fifty hepatitis A patient...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- QJM : monthly journal of the Association of Physicians
دوره 103 12 شماره
صفحات -
تاریخ انتشار 2010